Gene Therapy for Neurological Disorders and Brain Tumors
Steven A. Reeves (auth.), E. Antonio Chiocca MD, PhD, Xandra O. Breakefield PhD (eds.)
Drs. Chiocca and Breakefield bring together in Gene Therapy for Neurological Disorders and Brain Tumors many of the leading gene therapy researchers and clinicians to capture the breadth of the field-from basic vector technology to current and future clinical applications. The authoritative contributions provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorders, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea.
Gene Therapy for Neurological Disorders and Brain Tumors illuminates the rapidly developing applications of gene transfer technologies to the treatment of a wide range of neurological disorders and brain tumors. Readers will learn the current delivery methods for transgenes, will learn the characteristics of the transgene delivery vectors, and come to more fully understand gene therapies for both neuro-oncologic and neurologic disorders.